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Department of Pathology and Molecular Pathology
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Neurodegeneration.

  • Histopathological diagnostic criteria for Alzheimer's disease.
  • Topographical and lesion-specific evaluation in dementia and correlation with imaging, PET, and neuropsychological status.
  • Significance of SNPs (from GWAS studies) in neuropathologically confirmed Alzheimer's cases and correlation with neuropathological changes.
  • Molecular changes in demented patients without classical neuropathological alterations (i.e., amyloid plaques, NFT, Lewy bodies, FUS, TDP-43).
  • Splice variants in normal aging.