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Institute of Pharmacology
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Publications.

Most Recent Publication

  1. Luciano, M., ..., Steiner, P., ... and Horejs-Höck, J. 2024. Targeting NLRP3 inhibits AML progression by inducing PERK/elF2-mediated apoptosis. Cell Communication and Signaling. (doi.org/10.1186/s12964-024-01777-6)

  2. Steiner, P., Kerschbaum, H., Andosch, A., Melek, K. and Zierler, S. 2024. Thapsigargin induces a non-apoptotic alternative modality of programmed cell death in RBL-1 cells. Intrinsinc Activity. (doi:10.25006/IA.12.S1-A2.22)

  3. Steiner, P., Kerschbaum, H., Andosch, A., Melek, K. and Zierler, S. 2024. Thapsigargin induces non-apoptotic programmed cell death in RBL-1 cells. BIO Web of Conferences. (doi.org/10.1051/bioconf/202412916011, opens an external URL in a new window)

  4. Höger B., Madlmayr A., Hölting K., Nadolni W., Lewitz D., Haider T., Hampe S., Fraticelli M., Chubanov V., Sperandio M., Boekhoff I., Gudermann T., Zierler S.: TRPM7 ion channel and kinase drives AKT signaling and immune-cell activation, Intrinsic Activity, 2023 doi: 10.25006/IA.11.S1-A2.2, opens an external URL in a new window

  5. Steiner P., Andosch A., Kazemi M., Kern K., Madlmayr A., Oberascher K., Gudermann T., Boekhoff I., Bracher F., Keller M., Grimm C., Kerschbaum H., Zierler S.: Pharmacological inhibition of endolysosomal Ca2+ channels in immune cells and related (ultra)structural and physiological implications, Intrinsic Activity, 2023 doi: 10.25006/IA.11.S1-A2.30, opens an external URL in a new window

  6. Khajavi N., Beck A., Zierler S., Müller T., Gudermann T.: TRPM7 kinase modulates insulin production and compensatory islet response to obesogenic diet, in Springer Nature: 8th German Pharm-Tox Summit 2023, Serie Naunyn-Schmiedeberg's Archives of Pharmacology, 2023 doi: 10.1007/s00210-023-02397-6, opens an external URL in a new window

  7. Steiner P., Arlt E., Boekhoff I., Gudermann T., Zierler S.: TPC Functions in the Immune System, SpringerLink, Handbook of Experimental Pharmacology, 2023 doi: 10.1007/164_2022_634, opens an external URL in a new window

  8. Jooss T., Zhang J., Zimmer B., Rezzonico-Jost T., Rissiek B., Pelczar P., Seehusen F., Koch-Nolte F., Magnus T., Zierler S., Huber S., Schemann M., Grassi F., Nicke A.: Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system - no evidence for a role of neuronal P2X7 receptors in colitis., Science Direct, Mucosal Immunology, 2023 doi: 10.1016/j.mucimm.2022.11.003, opens an external URL in a new window

  9. Höger B., Nadolni W., Hampe S., Hoelting K., Fraticelli M., Zaborsky N., Madlmayr A., Sperrer V., Fraticelli L., Addington L., Steinritz D., Chubanov V., Geisberger R., Greil R., Breit A., Boekhoff I., Gudermann T., Zierler S.: Inactivation of TRPM7 Kinase Targets AKT Signaling and Cyclooxygenase-2 Expression in Human CML Cells, Oxford Academic, Function, 2023 doi: 10.1093/function/zqad053, opens an external URL in a new window

  10. Steiner P., Arlt E., Boekhoff I., Gudermann T., Zierler S.: Two-Pore Channels Regulate Inter-Organellar Ca2+ Homeostasis in Immune Cells, Cells, 2022 doi: 10.3390/cells11091465, opens an external URL in a new window

  11. Immler R., Nadolni W., Bertsch A., Morikis V., Rohwedder I., Masgrau-Alsina S., Schroll T., Yevtushenko A., Soehnlein O., Moser M., Gudermann T., Barnea E., Rehberg M., Simon S., Zierler S., Pruenster M., Sperandio M.: The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation, Oxford University Press, Cardiovascular Research, 2022 doi: 10.1093/cvr/cvab133, opens an external URL in a new window (Clarivate: Q1 95.12% - TOP 10%)

  12. Zeitlmayr S., Zierler S., Staab-Weijnitz C., Dietrich A., Geiger F., Horgen F., Gudermann T., Breit A.: TRPM7 restrains plasmin activity and promotes transforming growth factor-β1 signaling in primary human lung fibroblasts, SpringerLink, Archives of Toxicology, 2022 doi: 10.1007/s00204-022-03342-x, opens an external URL in a new window (Clarivate: Q1 92.57% - TOP 10%)

  13. Khajavi N., Beck A., Ricku K., Beyerle P., Jacob K., Syamsul S., Belkacemi A., Reinach P., Schreier P., Salah H., Popp T., Novikoff A., Breit A., Chubanov V., Müller T., Zierler S., Gudermann T.: TRPM7 kinase is required for insulin production and compensatory islet responses during obesity., JCI Insight, 2022 doi: 10.1172/jci.insight.163397, opens an external URL in a new window (Clarivate: Q1 93.42% - TOP 10%)

  14. Schmidt E., Narangoda C., Nörenberg W., Egawa M., Rössig A., Leonhardt M., Schaefer M., Zierler S., Kurnikova M., Gudermann T., Chubanov V.: Structural mechanism of TRPM7 channel regulation by intracellular magnesium, Cellular and Molecular Life Sciences, 2022 doi: 10.1007/s00018-022-04192-7, opens an external URL in a new window

  15. Rössig A., Hill K., Nörenberg W., Weidenbach S., Zierler S., Schaefer M., Gudermann T., Chubanov V.: Pharmacological agents selectively acting on the channel moieties of TRPM6 and TRPM7, Cell Calcium, 2022 doi: 10.1016/j.ceca.2022.102640, opens an external URL in a new window

  16. Spix B., Butz E., Chen C., Rosato A., Tang R., Jeridi A., Kudrina V., Plesch E., Wartenberg P., Arlt E., Briukhovetska D., Ansari M., Günsel G., Conlon T., Wyatt A., Wetzel S., Teupser D., Holdt L., Ectors F., Boekhoff I., Boehm U., García-Añoveros J., Saftig P., Giera M., Kobold S., Schiller H., Zierler S., Gudermann T., Wahl-Schott C., Bracher F., Yildirim A., Biel M., Grimm C.: Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice, Nature Communications, 2022 doi: 10.1038/s41467-021-27860-x, opens an external URL in a new window (Clarivate: Q1 95.15% - TOP 10%)

  17. Höger B., Zierler S.: Ion Channels and Transporters in Immunity—Where do We Stand?, in Oxford Academic, Function, 2022 doi: 10.1093/function/zqac070, opens an external URL in a new window

  18. Höger B., Zierler S.: Engulf and digest – TRPM7 as key regulator of macrophage phagosome maturation, in Science Direct, Cell Calcium, 2022 doi: 10.1016/j.ceca.2022.102636, opens an external URL in a new window

  19. Hollenhorst M., Nandigama R., Evers S., Gamayun I., Wadood N., Salah A., Pieper M., Wyatt A., Stukalov A., Gebhard A., Nadolni W., Burow W., Herr C., Beisswenger C., Kusumakshi S., Ectors F., Kichko T., Hübner L., Reeh P., Munder A., Wienhold S., Witzenrath M., Bals R., Flockerzi V., Gudermann T., Bischoff M., Lipp P., Zierler S., Chubanov V., Pichlmair A., König P., Boehm U., Krasteva-Christ G.: Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection, The Journal of Clinical Investigation, 2022 doi: 10.1172/JCI150951, opens an external URL in a new window (Clarivate: Q1 98.68% - TOP 10%)

  20. Michelini, Barbero, Prinelli, Steiner, Weiss, Verwanger, Andosch, Lütz-Meindl, Puntes, Drobne, Duschl, Horejs-Hoeck. Gold nanoparticles (AuNPs) impair LPS-driven immune responses by promoting a tolerogenic-like dendritic cell phenotype with altered endosomal structure. Nanoscale. 2021 doi: 10.1039/d0nr09153g.