Fahrner, M., Stadlbauer, M., Muik, M., Rathner, P., Stathopulos, P., Ikura, M., Muller, N., and Romanin, C. (2018) A dual mechanism promotes switching of the Stormorken STIM1 R304W mutant into the activated state, öffnet eine externe URL in einem neuen Fenster. Nat Commun 9, 825

Rathner, P., Stadlbauer, M., Romanin, C., Fahrner, M., Derler, I., and Muller, N. (2018) Rapid NMR-scale purification of (15)N,(13)C isotope-labeled recombinant human STIM1 coiled coil fragments, öffnet eine externe URL in einem neuen Fenster. Protein Expr Purif 146, 45-50

Derler, I., Butorac, C., Krizova, A., Stadlbauer, M., Muik, M., Fahrner, M., Frischauf, I., and Romanin, C. (2018) Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N terminus, öffnet eine externe URL in einem neuen Fenster. J Biol Chem 293, 1259-1270

Fahrner, M., Pandey, S. K., Muik, M., Traxler, L., Butorac, C., Stadlbauer, M., Zayats, V., Krizova, A., Plenk, P., Frischauf, I., Schindl, R., Gruber, H. J., Hinterdorfer, P., Ettrich, R., Romanin, C., and Derler, I. (2018) Communication between N terminus and loop2 tunes Orai activation, öffnet eine externe URL in einem neuen Fenster. J Biol Chem 293, 1271-1285

Fahrner, M., Stadlbauer, M., Muik, M., Rathner, P., Stathopulos, P., Ikura, M., Muller, N., and Romanin, C. (2018) A dual mechanism promotes switching of the Stormorken STIM1 R304W mutant into the activated state, öffnet eine externe URL in einem neuen Fenster. Nat Commun 9, 825

Frischauf, I., Litvinukova, M., Schober, R., Zayats, V., Svobodova, B., Bonhenry, D., Lunz, V., Cappello, S., Tociu, L., Reha, D., Stallinger, A., Hochreiter, A., Pammer, T., Butorac, C., Muik, M., Groschner, K., Bogeski, I., Ettrich, R. H., Romanin, C., and Schindl, R. (2017) Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription, öffnet eine externe URL in einem neuen Fenster. Sci Signal 10

Frischauf, I., Litvinukova, M., Schober, R., Zayats, V., Svobodova, B., Bonhenry, D., Lunz, V., Cappello, S., Tociu, L., Reha, D., Stallinger, A., Hochreiter, A., Pammer, T., Butorac, C., Muik, M., Groschner, K., Bogeski, I., Ettrich, R. H., Romanin, C., and Schindl, R. (2017) Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription, öffnet eine externe URL in einem neuen Fenster. Sci Signal 10

Traxler, L., Rathner, P., Fahrner, M., Stadlbauer, M., Faschinger, F., Charnavets, T., Muller, N., Romanin, C., Hinterdorfer, P., and Gruber, H. J. (2017) Detailed Evidence for an Unparalleled Interaction Mode between Calmodulin and Orai Proteins, öffnet eine externe URL in einem neuen Fenster. Angew Chem Int Ed Engl 56, 15755-15759

Fahrner, M., Schindl, R., Muik, M., Derler, I., and Romanin, C. (2017) The STIM-Orai Pathway: The Interactions Between STIM and Ora, öffnet eine externe URL in einem neuen Fensteri. Adv Exp Med Biol 993, 59-81

Poteser, M., Leitinger, G., Pritz, E., Platzer, D., Frischauf, I., Romanin, C., and Groschner, K. (2016) Live-cell imaging of ER-PM contact architecture by a novel TIRFM approach reveals extension of junctions in response to store-operated Ca(2+)-entry, öffnet eine externe URL in einem neuen Fenster. Sci Rep 6, 35656

Frischauf, I., Fahrner, M., Jardin, I., and Romanin, C. (2016) The STIM1: Orai Interaction, öffnet eine externe URL in einem neuen Fenster. Adv Exp Med Biol 898, 25-46

Derler, I., Jardin, I., and Romanin, C. (2016) Molecular mechanisms of STIM/Orai communication, öffnet eine externe URL in einem neuen Fenster. Am J Physiol Cell Physiol 310, C643-662

Derler, I., Jardin, I., Stathopulos, P. B., Muik, M., Fahrner, M., Zayats, V., Pandey, S. K., Poteser, M., Lackner, B., Absolonova, M., Schindl, R., Groschner, K., Ettrich, R., Ikura, M., and Romanin, C. (2016) Cholesterol modulates Orai1 channel function, öffnet eine externe URL in einem neuen Fenster. Sci Signal 9, ra10

Frischauf, I., Zayats, V., Deix, M., Hochreiter, A., Jardin, I., Muik, M., Lackner, B., Svobodova, B., Pammer, T., Litvinukova, M., Sridhar, A. A., Derler, I., Bogeski, I., Romanin, C., Ettrich, R. H., and Schindl, R. (2015) A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription, öffnet eine externe URL in einem neuen Fenster. Sci Signal 8, ra131

Maus, M., Jairaman, A., Stathopulos, P. B., Muik, M., Fahrner, M., Weidinger, C., Benson, M., Fuchs, S., Ehl, S., Romanin, C., Ikura, M., Prakriya, M., and Feske, S. (2015) Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation, öffnet eine externe URL in einem neuen Fenster. Proc Natl Acad Sci U S A 112, 6206-6211

Fahrner, M., Muik, M., Schindl, R., Butorac, C., Stathopulos, P., Zheng, L., Jardin, I., Ikura, M., and Romanin, C. (2014) A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1), öffnet eine externe URL in einem neuen Fenster. J Biol Chem 289, 33231-33244

Raphael, M., Lehen'kyi, V., Vandenberghe, M., Beck, B., Khalimonchyk, S., Vanden Abeele, F., Farsetti, L., Germain, E., Bokhobza, A., Mihalache, A., Gosset, P., Romanin, C., Clezardin, P., Skryma, R., and Prevarskaya, N. (2014) TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival., öffnet eine externe URL in einem neuen Fenster Proc Natl Acad Sci U S A 111, E3870-3879

Zhang, X., Zhang, W., Gonzalez-Cobos, J. C., Jardin, I., Romanin, C., Matrougui, K., and Trebak, M. (2014) Complex role of STIM1 in the activation of store-independent Orai1/3 channels., öffnet eine externe URL in einem neuen Fenster J Gen Physiol 143, 345-359

Stathopulos, P. B., Schindl, R., Fahrner, M., Zheng, L., Gasmi-Seabrook, G. M., Muik, M., Romanin, C., and Ikura, M. (2013) STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry, öffnet eine externe URL in einem neuen Fenster. Nat Commun 4, 2963

Romanin, C. (2013) In this issue of Channels: Special issue on STIM and Orai, öffnet eine externe URL in einem neuen Fenster. Channels (Austin) 7, 329

Fahrner, M., Derler, I., Jardin, I., and Romanin, C. (2013) The STIM1/Orai signaling machinery. Channels, öffnet eine externe URL in einem neuen Fenster (Austin) 7, 330-343

Konig, S., Browne, S., Doleschal, B., Schernthaner, M., Poteser, M., Machler, H., Wittchow, E., Braune, M., Muik, M., Romanin, C., and Groschner, K. (2013) Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle, öffnet eine externe URL in einem neuen Fenster. Am J Physiol Heart Circ Physiol 305, H1646-1657

Derler, I., Plenk, P., Fahrner, M., Muik, M., Jardin, I., Schindl, R., Gruber, H. J., Groschner, K., and Romanin, C. (2013) The extended transmembrane Orai1 N-terminal (ETON) region combines binding interface and gate for Orai1 activation by STIM1, öffnet eine externe URL in einem neuen Fenster. J Biol Chem 288, 29025-29034

Zhang, X., Gonzalez-Cobos, J. C., Schindl, R., Muik, M., Ruhle, B., Motiani, R. K., Bisaillon, J. M., Zhang, W., Fahrner, M., Barroso, M., Matrougui, K., Romanin, C., and Trebak, M. (2013) Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels, öffnet eine externe URL in einem neuen Fenster. Mol Cell Biol 33, 3715-3723

Lichtenegger, M., Stockner, T., Poteser, M., Schleifer, H., Platzer, D., Romanin, C., and Groschner, K. (2013) A novel homology model of TRPC3 reveals allosteric coupling between gate and selectivity filter, öffnet eine externe URL in einem neuen Fenster. Cell Calcium 54, 175-185

Kaya, L., Meissner, B., Riedl, M. C., Muik, M., Schwarzer, C., Ferraguti, F., Sarg, B., Lindner, H., Schweigreiter, R., Knaus, H. G., Romanin, C., and Bandtlow, C. E. (2013) Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons, öffnet eine externe URL in einem neuen Fenster. Biochim Biophys Acta 1833, 1421-1433

Gonzalez-Cobos, J. C., Zhang, X., Zhang, W., Ruhle, B., Motiani, R. K., Schindl, R., Muik, M., Spinelli, A. M., Bisaillon, J. M., Shinde, A. V., Fahrner, M., Singer, H. A., Matrougui, K., Barroso, M., Romanin, C., and Trebak, M. (2013) Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia, öffnet eine externe URL in einem neuen Fenster. Circ Res 112, 1013-1025

Stathopulos PB, Schindl R, Fahrner M, Zheng L, Gasmi-Seabrook GM, Muik M, Romanin C, Ikura M (2013) STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry, öffnet eine externe URL in einem neuen Fenster. Nature communications 4: 2963

Muik M, Fahrner M, Schindl R, Stathopulos P, Frischauf I, Derler I, Plenk P, Lackner B, Groschner K, Ikura M, Romanin C. (2011) STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation., öffnet eine externe URL in einem neuen Fenster The EMBO J 30:1678-89.

Schindl R, Frischauf I, Bergsmann J, Muik M, Derler I, Lackner B, Groschner K, Romanin C (2009) Plasticity in Ca2+ selectivity of Orai1/Orai3 heteromeric channel, öffnet eine externe URL in einem neuen Fenster. PNAS 106:19623-8.

Derler I, Fahrner M, Carugo O, Muik M, Bergsmann J, Schindl R, Frischauf I, Eshaghi S and Romanin C. (2009) Increased hydrophobicity at the N-terminus/membrane interface impairs gating of the SCID-related ORAI1 mutant, öffnet eine externe URL in einem neuen Fenster. J Biol Chem 284:15903-15915.

uik M, Fahrner M, Derler I, Schindl R, Bergsmann J, Frischauf I, Groschner K, Romanin C (2009) A cytosolic homomerization and a modulatory domain within STIM1 C terminus determine coupling to ORAI1 channels., öffnet eine externe URL in einem neuen Fenster J Biol Chem 284:8421-8426.

Muik M, Frischauf I, Derler I, Fahrner M, Bergsmann J, Eder P, Schindl R, Hesch C, Polzinger B, Fritsch R, Kahr H, Madl J, Gruber H, Groschner K, Romanin C (2008) Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation, öffnet eine externe URL in einem neuen Fenster. J Biol Chem 283:8014-8022.

Singh A, Hamedinger D, Hoda J.-C, Gebhart M, Koschak A, Romanin C, Striessnig J. (2006) C-terminal modulator controls Ca2+-dependent gating of Cav1.4 L-type Ca2+ channels, öffnet eine externe URL in einem neuen Fenster. Nature Neurosci 9:1108-1116.

H. Kahr, R. Schindl, R. Fritsch, B. Heinze, M. Hofbauer, M.A. Hack, M. A. Mörtelmaier, K. Groschner, J.-B. Peng, H. Takanaga, M. A. Hediger and C. Romanin (2004) CaT1 knock-down strategies fail to affect CRAC channels in mucosal-type mast cells, öffnet eine externe URL in einem neuen Fenster. J Physiol 557.1: 121-132.