Spix B., Butz E.S., Chen C.C., Plesch E., Wartenberg P., Scotto Rosato A., Arlt E., Briukhovetska D., Jeridi A., Wyatt A., Kissing S., Teupser D., Holdt L.M., Boehm U., García-Añoveros J., Saftig P., Schiller H.B., Kobold S., Boekhoff I., Zierler S., Wahl-Schott C., Gudermann G., Bracher F., Yildirim A.Ö., Biel M., Grimm C. Impaired MMP-12 clearance and emphysema-like phenotype in mucolipin 3 deficient mice. Nature Communications 2022, 13(1):318. doi: 10.1038/s41467-021-27860-x

Nadolni W., Immler R., Hoelting K., Fraticelli M., Ripphahn M., Rothmiller S., Matsushita M., Boekhoff I., Gudermann T., Sperandio M., Zierler S. TRPM7 Kinase is essential for Neutrophil Recruitment and Function via Regulation of Akt/mTOR Signaling. Frontiers in Immunology  2021 doi: 10.3389/fimmu.2020.606893

Arlt E., Fraticelli M., Tsvilovskyy V., O’Neill T.J., Wennemuth G., Breit A., Wahl-Schott C., Biel M., Freichel M., Grimm C., Gudermann T., Klugbauer N., Boekhoff I, Zierler S. Targeting the two-pore channel TPC1 augments systemic anaphylaxis and mast cell activity. Proceedings of the National Academy of Sciences of the United States of America 2020 117:18068-18078. doi: 10.1073/pnas.1920122117

Gerndt S., Chen C., Chao Y., Yuan Y., Burgstaller S., Scotto Rosato A., Krogsaeter E., Urban N., Jacob K., Nguyen O.N.P., Miller M.T., Keller M., Vollmar A.M., Gudermann T., Zierler S., Schredelseker J., Schaefer M., Biel M., Malli R., Wahl-Schott C., Bracher F., Patel S., Grimm C. Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function. eLife, 2020 doi: 10.7554/eLife.54712

Voringer S., Schreyer L., Nadolni W., Woerther K., Mittermeier C., Ferioli S., Singer S., Holzer K., Zierler S., Chubanov V., Liebl B., Gudermann T., Muehlich S., Targeted inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity. Oncogene 2019 doi: 10.1038/s41388-019-1140-8

Romagnani A, Vettore V, Rezzonico-Jost T., Hampe S., Rottoli E., Nadolni W., Perotti M., Geiger S., Wennemuth G., Recordati C., Matsushita M., Proietti M., Chubanov V., Gudermann T., Grassi F., Zierler S. TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut. Nature Communications 2017 8:1917. doi: 10.1038/s41467-017-01960-z

Zierler S., Sumoza-Toledo A., Suzuki S., O’Duill F., Ryazanova L.V., Penner R., Ryazanov A.G., Fleig A. TRPM7 kinase activity regulates murine mast cell degranulation. The Journal of Physiology 2016 594, 2957-70. doi: 10.1113/JP271564

Stritt S., Nurden P., Favier R., Favier M., Ferioli S., Gotru SK., van Eeuwijk JM., Schulze H., Nurden AT., Lambert MP., Turro E., Burger-Stritt S., MatsushitaM., Mittermeier L., Ballerini P., Zierler S., Laffan MA., Chubanov V., Gudermann T., Nieswandt B., Braun A. Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg²⁺ homeostasis and cytoskeletal architecture. Nature Communications 2016 29, 7:11097 doi: 10.1038/ncomms11097

Grossinger, EM., Weiss, L., Zierler, S., Rebhandl, S., Krenn, P. W., Hinterseer, E., Schmolzer, J., Asslaber, D., Hainzl, S., Neureiter, D., Egle, A., Pinon-Hofbauer, J., Hartmann, T. N., Greil, R., and Kerschbaum, H. H. Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade. Leukemia 2014 28:954-958, doi: 10.1038/leu.2014.37

Ryazanova, L. V., Rondon, L. J., Zierler, S., Hu, Z., Galli, J., Yamaguchi, T.P., Mazur, A., Fleig, A., Ryazanov, A.G. TRPM7 is essential for Mg²⁺ homeostasis in mammals. Nature Communications 2010 1:109, doi: 10.1038/ncomms1108